Plant Extracts Target Biofilms to Alleviate Nutritional and Metabolic Disorders in Animals

Area of Science:

• Veterinary Medicine
• Microbiology
• Pharmacology

Background:

• Bacterial biofilms cause persistent animal infections, leading to productivity losses and increased antibiotic use.
• Biofilm-induced inflammation and metabolic dysregulation contribute to nutritional disorders in veterinary settings.
• Conventional antibiotics are less effective against biofilms and can lead to resistance and toxic residues.

Purpose of the Study:

• To review the mechanisms of plant-derived compounds in modulating pathogenic bacterial biofilms.
• To explore the potential of plant extracts as a sustainable alternative to antibiotics in veterinary medicine.

Main Methods:

• Systematic narrative review of existing literature.
• Analysis of studies on plant extracts and their effects on bacterial biofilm formation and dispersal.
• Examination of direct and indirect mechanisms of action.

Main Results:

• Plant extracts exhibit multi-target actions against biofilms.
• Compounds from plant sources demonstrate favorable biocompatibility and metabolic regulatory potential.
• Plant-derived compounds can modulate biofilm formation and dispersal through various pathways.

Conclusions:

• Plant extracts represent a promising, sustainable strategy for managing bacterial biofilms in veterinary settings.
• These natural compounds offer a viable alternative to conventional antibiotics, mitigating risks of resistance and toxicity.
• Further research into plant-derived compounds can enhance animal health and food safety.