Related Experiment Video
Updated: May 5, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Cognitive impairment and its associated health conditions in American Indian communities
Wenjun Fan1, Jiahui Dai1, Yuxi Shi1
1Department of Epidemiology & Biostatistics, Joe C. Wen School of Population & Public Health, Susan and Henry Samueli College of Health Sciences, University of California, Irvine, CA USA.
Abstract:
This cross-sectional study examined cognitive impairment and its associations with health conditions among American Indian (AI) adults aged ≥55 residing in the Pacific Northwest, Rocky Mountains, and Northern Plains from 2019 to 2023. Subjective cognitive impairment was assessed using the adapted AD8, a culturally tailored eight-item measure to differentiate aging and dementia. Among 712 AI adults surveyed, 34.3% had cognitive impairment, with the highest proportion observed among those aged 55-59 (40.3%). Results from negative binomial regression indicated that distress [prevalence rate ratio (PRR) = 2.25, 95% confidence interval (CI): (1.31-3.87)], head injury [PRR = 1.58, 95% CI: (1.00-2.51)], and diabetes [PRR = 1.59, 95% CI: (1.21-2.10)] were significantly associated with worse cognitive performance. Additionally, the findings suggest a high prevalence of cognitive impairment in this AI sample of convenience. Furthermore, associations between several health conditions and cognitive function differ by age groups. Early screening for cognitive impairment using tools like AD8 is recommended for AI adults.
Related Concept Videos
Intellectual Disability
Alzheimer Disease l: Introduction
Dementia l: Introduction
Dementia
The progression of dementia is generally gradual....
Language and Cognition
Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...

