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Mediation analysis in longitudinal data: an unbiased estimator for cumulative indirect effect

Yi Li, Howard Cabral, Yorghos Tripodis

    Medrxiv : the Preprint Server for Health Sciences
    |May 4, 2026
    PubMed
    Summary

    This study introduces a new method for mediation analysis to understand how past and present exposures cumulatively impact health outcomes over time. The approach was used to show DNA methylation mediates alcohol

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