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Updated: May 5, 2026

Chemotherapy-induced Vascular Toxicity - Real-time In vivo Imaging of Vessel Impairment
Published on: January 7, 2015
Lower Limb Nonvisualization Caused by Macroarterial Thrombosis After Cervical Cancer TP Chemotherapy in Whole-body
Changping Liang1, Ming Li1, Hui Wang1
1Department of Nuclear Medicine, Panzhihua Municipal Central Hospital, Panzhihua, China.
Abstract:
A 68-year-old woman with cervical cancer and pulmonary metastases presented with limb paresthesia and pain one week after chemotherapy. Whole-body bone scintigraphy performed to evaluate for bone metastases revealed rib metastases, along with poor visualization of the right distal lower extremity, raising suspicion for possible arterial flow obstruction in the right lower limb. Further imaging confirmed extensive thrombosis in the right common iliac artery and its distal branches. This case suggests that decreased uptake in the skeletal structures and surrounding soft tissues on whole-body bone scintigraphy may indicate a risk of arterial thrombosis.
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