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Updated: May 5, 2026

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
Intense FDG Uptake of Lung Metastases From Succinate Dehydrogenase-deficient Renal Cell Carcinoma
Jun Zhang1, Aisheng Dong2, Yang Wang3
1Department of Cardiothoracic Surgery, The Second Affiliated Hospital, Jiaxing University, Jiaxing, Zhejiang.
Abstract:
Succinate dehydrogenase-deficient renal cell carcinoma is a rare and recently recognized distinct subtype of renal cell carcinoma. Usefulness of FDG PET/CT in the management of this tumor is rarely reported. We describe FDG PET/CT findings in a case of succinate dehydrogenase-deficient renal cell carcinoma with lung metastases. The lung metastases <2 cm showed high FDG uptake with SUV max of 19.1, which may be due to extreme Warburg effect resulting from succinate dehydrogenase mutation. This case indicates FDG PET/CT may be useful for detecting and staging of this novel tumor, which needs to be investigated in future studies.
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