Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

21
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial...
21

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development and validation of a LightGBM-based model with risk stratification for predicting early recurrence after catheter ablation for atrial fibrillation.

BMC cardiovascular disorders·2026
Same author

Non-Dipping Blood Pressure and Reduced Heart Rate Deceleration Capacities Are Associated With Malnutrition in Patients With Gastrointestinal Cancer.

Journal of clinical hypertension (Greenwich, Conn.)·2026
Same author

Krüppel-like factor 5 transcription factor is a positive regulator of NRG-1 in human coronary artery smooth muscle cells.

Cardiovascular journal of Africa·2026
Same author

Polyether antibiotics K-41A and K-41Am inhibit HIV-1 replication via suppressing the activities of HIV-1 reverse transcriptase and integrase.

Archives of medical science : AMS·2026
Same author

Heart Failure with Preserved Ejection Fraction as a Risk Factor for Atrial Fibrillation Recurrence after Ablation.

Cardiovascular drugs and therapy·2026
Same author

Optimizing planting depth and propagule characteristics for efficient cultivation of Pinellia ternata.

Scientific reports·2025
Same journal

Nasal Reconstruction Using a Synthetic Dermal Substitute: An Updated Algorithm and Clinical Outcomes.

The Journal of craniofacial surgery·2026
Same journal

Costochondral Graft Reconstruction of the Temporomandibular Joint: Long-Term Functional Outcomes and Growth-Related Complications.

The Journal of craniofacial surgery·2026
Same journal

3D-Printed Patient-Specific Polyetheretherketone (PEEK) Implants for Cranioplasty: A Retrospective Analysis of 50 Cases With Focus on Subcutaneous Fluid Collection Management.

The Journal of craniofacial surgery·2026
Same journal

Repair of a Congenital Isolated Alar Defect Using Mutaf Triangular Closure and Composite Ear Cartilage Graft in a Pediatric Patient.

The Journal of craniofacial surgery·2026
Same journal

Concepts of Facial Beauty: From Antiquity to the Era of AI-A Short Review.

The Journal of craniofacial surgery·2026
Same journal

Impact of Perioperative Opioid Prescriptions on Early and Late Complications After Rhinoplasty: A Propensity-Matched Study.

The Journal of craniofacial surgery·2026
See all related articles

Related Experiment Video

Updated: May 5, 2026

Author Spotlight: A Reproducible and Efficient Method for Accessing Porcine Brain via Craniectomy
04:26

Author Spotlight: A Reproducible and Efficient Method for Accessing Porcine Brain via Craniectomy

Published on: July 5, 2024

1.3K

Robot-Assisted Incision and Drainage for a Polymicrobial Brain Abscess.

Chun Gui1,2,3, Jiajia Li4, Qiqi Wang2,3,5

  • 1Departments of Emergency, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology.

The Journal of Craniofacial Surgery
|May 4, 2026
PubMed
Summary
This summary is machine-generated.

Robot-assisted surgery precisely drained a polymicrobial brain abscess in an eloquent area. Metagenomic sequencing guided targeted antibiotics, leading to significant neurological recovery and lesion resolution.

Keywords:
Brain abscesscentral regionmetagenomic next-generation sequencingodontogenic infectionpolymicrobial infectionrobotic surgery

More Related Videos

Implementation of Minimally Invasive Brain Tumor Resection in Rodents for High Viability Tissue Collection
08:23

Implementation of Minimally Invasive Brain Tumor Resection in Rodents for High Viability Tissue Collection

Published on: May 9, 2022

4.6K
Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis
03:42

Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis

Published on: March 15, 2024

1.6K

Related Experiment Videos

Last Updated: May 5, 2026

Author Spotlight: A Reproducible and Efficient Method for Accessing Porcine Brain via Craniectomy
04:26

Author Spotlight: A Reproducible and Efficient Method for Accessing Porcine Brain via Craniectomy

Published on: July 5, 2024

1.3K
Implementation of Minimally Invasive Brain Tumor Resection in Rodents for High Viability Tissue Collection
08:23

Implementation of Minimally Invasive Brain Tumor Resection in Rodents for High Viability Tissue Collection

Published on: May 9, 2022

4.6K
Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis
03:42

Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis

Published on: March 15, 2024

1.6K

Area of Science:

  • Neurosurgery
  • Infectious Diseases
  • Medical Robotics

Background:

  • Brain abscesses in eloquent areas pose significant management challenges.
  • Polymicrobial infections complicate treatment, often requiring advanced diagnostic and surgical approaches.
  • Failure of empirical antibiotic therapy necessitates alternative interventions.

Purpose of the Study:

  • To assess the clinical utility of robot-assisted incision and drainage for a complex brain abscess.
  • To evaluate the role of metagenomic next-generation sequencing (mNGS) in guiding antimicrobial therapy.
  • To report the outcomes of minimally invasive surgery for an eloquent-area brain abscess.

Main Methods:

  • Retrospective analysis of a single case involving a 71-year-old male with a polymicrobial brain abscess.
  • Robot-assisted (Remebot) navigation for precise abscess incision and drainage.
  • Postoperative mNGS of purulent material for pathogen identification.
  • Tailored antibiotic therapy based on mNGS results, supplemented with rehabilitation and hyperbaric oxygen therapy.

Main Results:

  • mNGS identified a polymicrobial infection including Fusobacterium nucleatum, Streptococcus constellatus, Parvimonas micra, and Porphyromonas gingivalis.
  • Robot-assisted drainage yielded thick purulent material.
  • Neurological recovery was significant, with return to grade 5 muscle strength and mild residual fine-motor impairment.
  • Follow-up MRI at three months showed complete resolution of intracranial ring-enhancing lesions.

Conclusions:

  • Robot-assisted incision and drainage is a safe, precise, and effective minimally invasive option for eloquent-area brain abscesses progressing despite medical management.
  • mNGS-guided targeted antimicrobial therapy is crucial for favorable outcomes in complex brain abscess infections.
  • This approach offers a valuable alternative for challenging neurosurgical cases.