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Related Concept Videos

Imaging Studies I: Kidney, Ureter, and Bladder Studies01:28

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Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
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Imaging Studies V: Intravenous Urography and Retrograde Pyelography01:22

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IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...
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Imaging Studies VII: Vascular Imaging01:19

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DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
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Imaging Studies VI: Voiding Cystourethrography and Cystography01:22

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Voiding Cystourethrography (VCUG) and Cystography are specialized radiographic procedures used to examine the structure and function of the bladder and urethra.Voiding Cystourethrography (VCUG)A Voiding Cystourethrogram (VCUG) is a diagnostic imaging procedure that assesses the anatomy and function of the lower urinary tract. It focuses on the bladder, bladder neck, and urethra, helping detect abnormalities such as vesicoureteral reflux (VUR)—the backward or reverse flow of urine into the...
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Related Experiment Video

Updated: May 6, 2026

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
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Quantitative imaging for assessing uveitis activity: A comprehensive review.

Amin Nabavi1, Mohammad Zarei2, Avik Shome3

  • 1Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami, Miami, FL, USA.

Survey of Ophthalmology
|May 4, 2026
PubMed
Summary
This summary is machine-generated.

Quantitative ocular imaging offers objective measures for uveitis activity assessment, moving beyond subjective clinical grading. These advanced techniques provide repeatable and reproducible data for improved treatment guidance and outcome monitoring.

Keywords:
Artificial intelligenceBiomarkersDisease activityFluorescein angiographyIndocyanine green angiographyOCTOCTAQuantitative imagingUveitis

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Inflammatory Diseases

Background:

  • Uveitis activity assessment is crucial for treatment and monitoring.
  • Current methods are subjective and lack standardization.
  • Ocular imaging advances enable quantitative, objective assessment.

Purpose of the Study:

  • To review current quantitative imaging strategies for uveitis activity.
  • To discuss applications, limitations, and future directions.
  • To highlight the shift from qualitative to quantitative uveitis assessment.

Main Methods:

  • Optical coherence tomography (OCT) for anterior chamber and vitreous inflammation.
  • OCT angiography (OCTA) for retinal vascular assessment.
  • Quantitative fundus fluorescein angiography for leakage and non-perfusion.
  • OCT for retinal tissue and choroidal biomarkers.
  • Peripapillary OCT and OCTA for optic nerve assessment.
  • AI-based grading systems and composite indices.

Main Results:

  • OCT provides surrogates for inflammatory cell count and haze.
  • OCTA assesses retinal vascular density and choroidal flow.
  • Quantitative angiography measures leakage and non-perfusion.
  • Retinal and choroidal biomarkers offer insights into disease.
  • Automated pipelines are evolving, but require validation.

Conclusions:

  • Quantitative ocular imaging provides objective endpoints for uveitis.
  • Standardization and validation are essential for clinical translation.
  • Future research should focus on reproducible, AI-driven assessment tools.