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Related Experiment Video

Updated: May 6, 2026

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
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Cardiovascular Risks Associated With Cannabis Use Among ED Patients.

Jeffrey T Bowcutt1, Brandon A Lopez1, Lauren G Bothwell2

  • 1Department of Emergency Medicine, University of Texas Medical Branch at Galveston, Galveston, USA.

Cureus
|May 5, 2026
PubMed
Summary
This summary is machine-generated.

Cannabis Use Disorder (CUD) is linked to higher mortality and myocardial infarction (MI) risks in emergency department patients. This study highlights the cardiovascular implications of cannabis use over three years.

Keywords:
alcohol related disorderscannabis use disordercardiovascular diseaseemergency medicinemarijuana

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Area of Science:

  • Cardiology
  • Public Health
  • Addiction Medicine

Background:

  • Cannabis Use Disorder (CUD) affects many adults, but its link to cardiovascular disease (CVD) is debated.
  • Existing research on cannabis and CVD yields inconsistent results.

Purpose of the Study:

  • To investigate the association between CUD and CVD outcomes in emergency department (ED) patients.
  • To compare CVD risks in CUD patients versus those without CUD and those with alcohol-related disorders (ARD).

Main Methods:

  • Retrospective analysis of 67 US healthcare organizations (TriNetX database, 2005-2022).
  • Propensity-matched comparison of adult ED patients with and without CUD.
  • Outcomes assessed: all-cause mortality, stroke, and myocardial infarction (MI) within three years post-ED visit.

Main Results:

  • Patients with CUD showed significantly higher rates of mortality (RR 1.69) and MI (RR 1.07) compared to non-CUD patients.
  • No significant difference in stroke rates was observed between CUD and non-CUD groups.
  • In secondary analysis, CUD patients had lower mortality but higher stroke and MI rates than ARD patients.

Conclusions:

  • Cannabis use is associated with increased risks of mortality and MI within three years of an ED visit.
  • Findings contribute to understanding the cardiovascular impact of cannabis.
  • Results may inform public health policy and clinical practice regarding CUD management.