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Related Concept Videos

Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

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Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
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Mitral Stenosis III: Medical Management01:26

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Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
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Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
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Surgically Managed Deep Sternal Wound Infection After Heart Transplantation.

Jeng-Wei Chen1,2, Heng-Wen Chou1,2, Chuan-I Tsao1

  • 1Department of Surgery, National, Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan (ROC).

Transplant Infectious Disease : an Official Journal of the Transplantation Society
|May 5, 2026
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Deep sternal wound infection after heart transplantation is rare but serious, linked to longer surgeries and worse survival. Microbiology is diverse, requiring careful interpretation of outcomes.

Keywords:
fungal infectionheart transplantationmediastinitisoutcomesventricular assist device

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Area of Science:

  • Cardiology
  • Infectious Diseases
  • Surgical Complications

Background:

  • Deep sternal wound infection (DSWI) is a significant complication post-heart transplantation (HT).
  • Limited data exists on DSWI microbiology and outcomes following HT.

Purpose of the Study:

  • To characterize the incidence, microbiology, management, and outcomes of DSWI after HT.
  • To identify factors associated with DSWI occurrence in HT recipients.

Main Methods:

  • Retrospective analysis of 298 HT recipients (2010-2023).
  • Stratification into DSWI (n=21) and uncomplicated sternal healing (n=277) groups.
  • Logistic regression used to identify factors associated with DSWI; microbiologic findings described.

Main Results:

  • DSWI cases showed longer graft ischemic time and cardiopulmonary bypass (CPB) duration.
  • Ischemic time and CPB time were independently associated with DSWI.
  • DSWI was linked to worse long-term survival; fungal infections showed poor outcomes but require cautious interpretation.

Conclusions:

  • DSWI after HT is infrequent but serious, associated with increased operative burden and reduced long-term survival.
  • Microbiologic findings in DSWI are heterogeneous.
  • Pathogen-specific outcome patterns need cautious interpretation due to sample size and mixed infections.