Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Global Socioeconomic Context and Brain Ageing in Epilepsy: an ENIGMA-Epilepsy study.

medRxiv : the preprint server for health sciences·2026
Same author

Beyond Broca and Wernicke: Epilepsy surgery in the language areas.

Epileptic disorders : international epilepsy journal with videotape·2026
Same author

Human parechovirus infection in neonates and young infants: Clinical features, diagnostic challenges, and neurodevelopmental outcomes.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology·2026
Same author

Pediatric sensorimotor cortical responsiveness to intracerebral stimulation during stereoelectroencephalographic monitoring: Age effects and area specificity.

Epilepsia·2026
Same author

Seizures and Apneas as clinical manifestations of brain lesions in term infants: a single center experience.

Italian journal of pediatrics·2026
Same author

Recommendations for structural magnetic resonance imaging in infants with first afebrile seizure or new onset epilepsy: Evidence-based recommendations from the ILAE Neuroimaging Task Force.

Epilepsia·2026

Related Experiment Video

Updated: May 7, 2026

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
09:57

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

Published on: September 20, 2024

3.5K

Electrical Source Imaging in Stereoelectroencephalography: A Proof-of-Concept Study.

Luca Bosisio1,2, Matteo Cataldi2, Domenico Tortora3

  • 1Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Child and Maternal Health (DINOGMI), University of Genoa, Genoa, Italy.

Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society
|May 5, 2026
PubMed
Summary
This summary is machine-generated.

Electrical source imaging (ESI) accurately pinpoints brain activity using stereoelectroencephalography (SEEG) data. Standardized low-resolution electromagnetic tomography (sLORETA) demonstrated superior performance for precise source localization in epilepsy research.

Keywords:
ESIElectrical source imagingEpilepsy surgerySEEG

More Related Videos

Brain Source Imaging in Preclinical Rat Models of Focal Epilepsy using High-Resolution EEG Recordings
08:20

Brain Source Imaging in Preclinical Rat Models of Focal Epilepsy using High-Resolution EEG Recordings

Published on: June 6, 2015

17.5K
Detecting Pre-Stimulus Source-Level Effects on Object Perception with Magnetoencephalography
09:25

Detecting Pre-Stimulus Source-Level Effects on Object Perception with Magnetoencephalography

Published on: July 26, 2019

7.4K

Related Experiment Videos

Last Updated: May 7, 2026

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
09:57

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization

Published on: September 20, 2024

3.5K
Brain Source Imaging in Preclinical Rat Models of Focal Epilepsy using High-Resolution EEG Recordings
08:20

Brain Source Imaging in Preclinical Rat Models of Focal Epilepsy using High-Resolution EEG Recordings

Published on: June 6, 2015

17.5K
Detecting Pre-Stimulus Source-Level Effects on Object Perception with Magnetoencephalography
09:25

Detecting Pre-Stimulus Source-Level Effects on Object Perception with Magnetoencephalography

Published on: July 26, 2019

7.4K

Area of Science:

  • Neuroscience
  • Medical Imaging
  • Epileptology

Background:

  • Electrical Source Imaging (ESI) traditionally uses scalp EEG but shows potential for intracerebral recordings.
  • Stereoelectroencephalography (SEEG) provides direct intracerebral data, offering a unique opportunity to evaluate ESI.
  • Accurate source localization is crucial for understanding brain function and treating neurological disorders like epilepsy.

Purpose of the Study:

  • To systematically evaluate the source localization accuracy of ESI when applied to SEEG data.
  • To compare the performance of different inverse solution methods for ESI with SEEG.
  • To determine the most effective ESI method for intracerebral source localization.

Main Methods:

  • Three inverse solution methods (sLORETA, MNE, dSPM) were compared.
  • Localization accuracy was assessed by measuring the distance between the stimulation site and the estimated source peak.
  • The study involved 12 subjects undergoing SEEG, localizing stimulation artifacts.

Main Results:

  • Standardized low-resolution electromagnetic tomography (sLORETA) exhibited the highest localization accuracy.
  • Mean localization error was 11.65 mm for single stimuli, improving to 9.28 mm when averaging 10 stimuli.
  • Subcentimeter accuracy was achieved in 77.5% of averaged trials, with sLORETA maintaining accuracy even with increasing distance from SEEG contacts.

Conclusions:

  • ESI is a viable method for accurate source localization using SEEG data.
  • sLORETA proved to be the most effective inverse solution method tested.
  • This approach can enhance spatial interpretability in complex epilepsy cases, especially with limited spatial sampling.