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Related Concept Videos

What are Lipids?01:38

What are Lipids?

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Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
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Lipids as Anchors01:32

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In the plasma membrane, the lipids forming the bilayer can also act as an anchor to tether proteins to the membrane. The three main types of lipid anchors found in eukaryotes are – prenyl groups, fatty acyl groups, and glycosylphosphatidylinositol or GPI groups. Prenyl and fatty acyl groups act as anchors on the cytosolic surface of the membrane, whereas GPI anchors proteins on the extracellular side.
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Related Experiment Video

Updated: May 7, 2026

Sample Preparation for Rapid Lipid Analysis in Drosophila Brain Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging
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LIPID MAPS: Powering discovery in lipidomics.

Lauren Cockayne1, Matthew J Conroy1, Chetin Baloglu2

  • 1Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff, Wales, UK.

Science Signaling
|May 5, 2026
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Summary
This summary is machine-generated.

Lipid research has advanced significantly over 25 years, with innovations enhancing the study of life-critical biomolecules. The LIPID MAPS resource offers open-access data, tools, and education for researchers.

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Area of Science:

  • Lipidomics
  • Biochemistry
  • Bioinformatics

Background:

  • Lipidomics has matured over 25 years, evolving from basic research to complex biological studies.
  • Understanding lipids is crucial due to their diverse roles in cellular functions and disease.

Purpose of the Study:

  • To review the maturation of lipid research and highlight innovations in studying biomolecules.
  • To showcase the ELIXIR Core Data Resource LIPID MAPS as a key community asset.

Main Methods:

  • Review of lipid research advancements.
  • Highlighting innovations in lipid analysis and data management.
  • Showcasing the LIPID MAPS database, software, and educational resources.

Main Results:

  • Lipid research has seen substantial growth and innovation.
  • The LIPID MAPS resource provides valuable open-access tools and data.
  • Community-driven resources are essential for advancing lipid science.

Conclusions:

  • Lipidomics is a rapidly advancing field with significant potential.
  • Open-access resources like LIPID MAPS are vital for supporting researchers.
  • Continued innovation and collaboration will drive future discoveries in lipid biology.