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Nanoparticles for colorectal cancer therapy: A review
Cong-Wen Yang1, Hong-Ming Fang1, Xiao-Yan Gong1
1State Key Laboratory of Refractories and Metallurgy, Key Laboratory of Coal Conversion & New Carbon Materials of Hubei Province, School of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan, 430081, China.
None:
Colorectal cancer (CRC) is one of the most common malignancies worldwide and is the second leading cause of cancer-related deaths. Currently, the main therapies for CRC include surgery, chemotherapy and radiotherapy. However, all of them have certain limitations, such as the tendency to trigger cancer recurrence and metastasis, and excessive damage to patients' bodies. To overcome some of these limitations, scholars have developed many nanoparticle-based therapies. This review discusses recent advances in the application of nanoparticles in CRC therapy, presenting the progress of inorganic, organic, inorganic-organic hybrid, and bioactive nanoparticles in the diagnosis and treatment of CRC. Finally, we also present our perspectives on the development of nanoparticles in CRC therapy.
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