Related Experiment Video
Updated: May 7, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Adrenocortical oncocytoma exhibits distinct biological features from renal oncocytoma: A rare case report
Mitsuhiro Tachibana1, Hiromichi Nakagawa2, Hayato Nozawa3
1Department of Diagnostic Pathology, Shimada General Medical Center, Shimada, Shizuoka, 427-8502, Japan.
Abstract:
Adrenocortical oncocytoma is a rare adrenal tumor. We report a 59-year-old Japanese woman with a right adrenal mass. The resected specimen showed a well-defined, mahogany-brown tumor measuring 4.3 cm. Microscopically, the tumor scored 0 under both the Lin-Weiss-Bisceglia system and the reticulin algorithm, indicating benignity. Immunohistochemical analysis revealed that tumor cells were positive for mitochondria and negative for BSND and ATP6V1G3. Ultrastructural examination found no uniform mitochondria in the cytoplasm of the tumor cells. The oncocytoma in this case may share more characteristics with an adrenal cortical adenoma than with a renal oncocytoma.
Related Concept Videos
Anatomy of the Adrenal Glands
These glands possess a distinctive yellow tinge due to the stored cholesterol and fatty acids required for hormone synthesis. They are encased in a fibrous capsule and cushioned by fat.
The adrenal gland comprises two distinct...
Cushing Syndrome II: Pathophysiology
Adrenal Gland Disorders
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Cushing Syndrome I: Introduction
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
External Anatomy of the Kidney
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...

