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First-in-Human Treatment of Medically Refractory Idiopathic Intracranial Hypertension With the eShunt System: Case

Pedro Lylyk1, Ivan Lylyk1, Carlos Bleise1

  • 1Division of Neurosurgery, ENERI Medical Institute, Equipo de Neurocirugia Endovascular y Radiologia Intervencionista, Buenos Aires, Argentina (P.L., I.L., C.B., E.S., P.N.L.).

Stroke (Hoboken, N.J.)
|May 6, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
cerebrospinal fluid pressurecerebrospinal fluid shuntsendovascular procedureshypertensionintracranialminimally invasive surgical proceduressubarachnoid space

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Increased Intracranial Pressure l: Introduction01:14

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Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component...
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