Related Experiment Video
Updated: May 7, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Suspected Cardioembolic Stroke Linked to Left Atrial Stunning After Pulsed Field Ablation for Atrial Fibrillation
Akinori Matsushima1, Takamichi Katsuhara2, Tomonobu Kodama2
1Division of Cardiology, Department of Medicine Nihon University School of Medicine Tokyo Japan.
Insights
A patient experienced ischemic stroke after pulmonary vein isolation. Pathology revealed a red thrombus, suggesting left atrial stunning caused clot formation during the cardiac ablation procedure.
Area of Science:
- Cardiology
- Neurology
- Pathology
Background:
- Cardiac ablation procedures, such as pulmonary vein isolation, are used to treat atrial arrhythmias.
- Ischemic stroke is a potential complication following cardiac procedures.
- Left atrial stunning is a transient dysfunction of the left atrium.
Purpose of the Study:
- To investigate the cause of ischemic stroke in a patient post-cardiac ablation.
- To analyze the pathological characteristics of the thrombus retrieved from the carotid artery.
Main Methods:
- A patient underwent pulsed field ablation for pulmonary vein and posterior wall isolation.
- The patient subsequently developed an ischemic stroke due to left carotid artery occlusion.
- Pathological examination of the retrieved thrombus was performed.
Main Results:
- The retrieved thrombus was characterized as an acute red thrombus.
- The findings suggest a link between left atrial stunning and thrombus formation.
Conclusions:
- Left atrial stunning following cardiac ablation may lead to thrombus formation and subsequent ischemic stroke.
- Prompt pathological analysis is crucial for understanding stroke etiology after ablation.
Abstract:
After pulsed field ablation with pulmonary vein and posterior wall isolation, a patient developed ischemic stroke due to left carotid artery occlusion. Pathology of the retrieved thrombus revealed an acute red thrombus, suggesting left atrial stunning-induced thrombus formation.
Related Concept Videos
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Acute Coronary Syndrome I: Introduction

