Staged endoscopic submucosal dissection of synchronous multiple early esophageal cancers for stricture prevention

Synchronous multiple lesions are not uncommon in patients with early esophageal cancer. Endoscopic submucosal dissection (ESD) provides an effective and safe treatment while preserving esophageal integrity. Single session ESD is generally performed for synchronous multiple early esophageal cancers, offering the advantage of reduced medical costs. However, when the lesions are adjacent, extensive mucosal defect after ESD increases the risk of refractory stricture. In this case, we described a strategy-staged ESD for the prevention of stricture following extensive resection of synchronous multiple early esophageal cancers.