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Symptom Series: Anorexia and Cachexia.

Elizabeth Schack¹, Elizabeth Capano¹

¹Elizabeth Schack, GNP-BC, ACHPN, New York Presbyterian Hospital/Weill Cornell Medical Center, New York, NY.

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|May 6, 2026

Summary

This summary is machine-generated.

Anorexia/cachexia syndrome in advanced illness presents challenges due to unclear guidelines and knowledge gaps. Palliative care providers are crucial for a multidisciplinary approach to manage this complex condition.

Keywords:

anorexia appetite stimulants cachexia loss of appetite malnutrition multimodal treatment palliative care syndrome wasting

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Area of Science:

Palliative Care
Oncology
Geriatrics

Background:

Anorexia/cachexia syndrome is a significant concern in advanced and terminal illnesses.
Management is hindered by a lack of clear definitions, guidelines, and consistent strategies.
Knowledge deficits exist among healthcare professionals and families regarding this complex syndrome.

Purpose of the Study:

To highlight the challenges in assessing and managing anorexia/cachexia syndrome.
To emphasize the pivotal role of palliative care providers in addressing this syndrome.
To advocate for a holistic, multidisciplinary approach coordinated by palliative care.

Main Methods:

Literature review focusing on assessment and management strategies.
Analysis of obstacles in current clinical practice.
Discussion of the evidence guiding palliative care interventions.

Main Results:

The syndrome's assessment and management are complicated by numerous obstacles.
Palliative care providers are essential leaders in understanding and applying evidence-based care.
A multidisciplinary approach is necessary for effective management.

Conclusions:

Palliative care nurses are well-positioned to coordinate multidisciplinary care for anorexia/cachexia.
Addressing this syndrome requires a holistic response to its complex impact.
Improved understanding and standardized guidelines are needed for better patient outcomes.