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Updated: May 8, 2026

High Throughput Image-Based Phenotyping for Determining Morphological and Physiological Responses to Single and Combined Stresses in Potato
Published on: June 7, 2024
StWRKY46 promotes stomatal closure and enhances potato drought tolerance by mediating the
Han Wei1,2, Xiao Wang1,2, Shigui Li1,3
1State Key Laboratory of Aridland Crop Science, Gansu Agricultural University, Lanzhou 730070, China.
Abstract:
Drought stress affects crop yield and quality. Abscisic acid (ABA) plays a crucial role in plant responses to drought stress; however, the signal transduction mechanism in potato (Solanum tuberosum L.) remains unclear. This study identifies a WRKY transcription factor (TF) member, StWRKY46, that enhances drought tolerance in potato. Under drought, StWRKY46 binds directly to the promoter of StPYL1 (a PYR/PYL family ABA receptor) and activates its transcription, triggering the ABA signaling pathway and improving drought tolerance in potato. StPYL1 interacts with StHAB1, StPP2C24, StPP2C51.1, and StABI2. StABI2 acts as a key negative regulator of ABA signaling. It interacts with StOST1, StSnRK2.5, and StSnRK2.6 to regulate the expression of stomatal movement-related genes, including the slow-type anion channel 1 (StSLAC1) and guard cell hydrogen peroxide-resistant 1 (StGHR1), thereby potentiating ABA-induced stomatal closure. Overall, our findings demonstrate the molecular mechanism of StWRKY46-mediated drought tolerance through the ABA-StPYL1-StABI2-StOST1/StSnRK2.5/StSnRK2.6 pathway in potato.
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