Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Implications of basal ganglionic dysfunction for schizophrenia.

T I Lidsky, P M Weinhold, F M Levine

    Biological Psychiatry
    |February 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The Empirical Anchor Technique : A Simple Experimental Method For Testing The Construct Validity Of Factor Titles.

    Multivariate behavioral research·2016
    Same author

    Adverse effects of childhood lead poisoning: the clinical neuropsychological perspective.

    Environmental research·2006
    Same author

    Inhibition of progenitor cell proliferation in the dentate gyrus of rats following post-weaning lead exposure.

    Neurotoxicology·2004
    Same author

    Enriched environment during development is protective against lead-induced neurotoxicity.

    Brain research·2001
    Same author

    Persisting insomnia following traumatic brain injury.

    The Journal of neuropsychiatry and clinical neurosciences·1999
    Same author

    Behavioural context and a distributed system: metabolic mapping studies of the basal ganglia.

    Canadian journal of experimental psychology = Revue canadienne de psychologie experimentale·1999
    Same journal

    Impact of Transcranial Direct Current Stimulation-Induced Electric Fields on Slowing Cognitive Decline in Older Adults With Mild Cognitive Impairment or Remitted Major Depressive Disorder: An Analysis of the PACt-MD Randomized Clinical Trial.

    Biological psychiatry·2026
    Same journal

    Remembering Jon-Kar Zubieta, M.D., Ph.D.

    Biological psychiatry·2026
    Same journal

    Kappa opioid receptor availability in borderline personality disorder: An in-vivo investigation with [<sup>11</sup>C]EKAP PET imaging.

    Biological psychiatry·2026
    Same journal

    From Satiety to Substance Use: Neural Mechanisms of GLP-1 Signaling in Appetite and Reward.

    Biological psychiatry·2026
    Same journal

    Distinct and Shared Molecular Mechanisms Underlie Morphological-Functional Overcoupling and Undercoupling in Major Depressive Disorder.

    Biological psychiatry·2026
    Same journal

    Dynamic Brain States With Cannabis Intoxication: Beyond "More Is Better" in Interpreting Brain Connectivity.

    Biological psychiatry·2026
    See all related articles

    This study suggests the basal ganglia play a key role in schizophrenia. Evidence links basal ganglia function to cognitive, affective, and attention deficits seen in schizophrenia, supporting this hypothesis.

    Area of Science:

    • Neuroscience
    • Psychiatry

    Background:

    • Schizophrenia presents with cognitive, affective, and attentional deficits.
    • Motor problems are common in psychiatric patients and linked to basal ganglia issues.

    Purpose of the Study:

    • To present evidence for the basal ganglia's involvement in mediating schizophrenia.
    • To explore the connection between basal ganglia dysfunction and schizophrenia symptoms.

    Main Methods:

    • Review of experimental and clinical literature.
    • Analysis of data linking basal ganglia function to cognitive and motor processes.

    Main Results:

    • Basal ganglia are implicated in higher cognitive processes, affect, and attention.
    • Schizophrenia symptoms align with deficits in these basal ganglionic functions.

    Related Experiment Videos

  • Pathological conditions of the basal ganglia manifest psychiatric symptoms.

    • Conclusions:

    • Dysfunction of the basal ganglia is a significant factor in schizophrenia.
    • The basal ganglia's role in cognitive and motor functions is crucial for understanding schizophrenia.