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Updated: May 8, 2026

Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer
Published on: March 14, 2019
Oncogenicity and Therapeutic Implications of Molecular Biomarkers in Colorectal Carcinoma
Mark G Evans1, Jaclyn F Hechtman1
1Department of Molecular Pathology, Caris Life Sciences, Phoenix, AZ, USA.
Abstract:
Colorectal carcinoma (CRC) is the most prevalent malignancy of the gastrointestinal tract and remains a leading cause of cancer-related illness and death worldwide. Recently, new treatment strategies have emerged with the identification of important biomarkers in CRC. As the emphasis on precision medicine in oncology intensifies, testing tumor specimens for key genomic alterations is becoming standard-of-care. This article seeks review the key molecular changes in CRC with important therapeutic implications.
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