Related Experiment Video
Updated: May 8, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
Laryngopharyngeal Reflux and Chronic Cough
Gabriela L Lilly1, Thomas L Carroll2
1Department of Otolaryngology - Head and Neck Surgery, Northwest Clinic for Voice and Swallowing, Oregon Health and Science University, Portland, OR, USA.
None:
Laryngopharyngeal reflux (LPR) is one of the most common causes of cough. It may not respond to acid suppression trials because non-acidic and weakly acidic reflux are often the etiology in refractory cases. Hypopharyngeal-esophageal multichannel intraluminal impedance with dual pH testing is the gold standard to diagnose LPR and guide personalized treatment of individual patients. Treatments typically involve a combination of barrier agents such as sodium alginate-based agents, acid suppression (when indicated), and diet and lifestyle management.
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