High-quality telomere-to-telomere genome assembly of the critically endangered tree Magnolia longipedunculata

Xin-Feng Wang1,2,3, Tong-Jian Liu1,2,3, Yi-Bing Wang1,2,3

  • 1State Key Laboratory of Plant Diversity and Specialty Crops, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, Guangdong, 510650, China.

Scientific Data
|May 6, 2026
PubMed

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Telomeres and Telomerase02:41

Telomeres and Telomerase

In eukaryotic DNA replication, a single-stranded DNA fragment remains at the end of a chromosome after the removal of the final primer. This section of DNA cannot be replicated in the same manner as the rest of the strand because there is no 3’ end to which the newly synthesized DNA can attach. This non-replicated fragment results in gradual loss of the chromosomal DNA during each cell duplication. Additionally, it can induce a DNA damage response by enzymes that recognize single-stranded DNA.