Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bioreactor Controls-II

Bioreactor Controls-II

In aerobic fermentations, oxygen is vital for microbial growth and metabolite production. Since air comprises only about 20% oxygen and the gas is poorly soluble in water—just 9 ppm at 20°C—supplying sufficient oxygen becomes a critical challenge, especially in high-demand processes like yeast growth or citric acid production. Even a fully saturated broth may offer only a few seconds of oxygen availability.To address this, sterile or scrubbed air is introduced into the fermentor via a sparger...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A Modified "Cross-Stitch" Suturing Technique Is Associated with Shorter Warm Ischemia Time in Robot-Assisted Partial Nephrectomy.

Journal of endourology·2026

Same author

Drought and Nitrogen Deposition Drive Community Restructuring of Endophytic Fungi and Functional Regulation by Dark Septate Endophytes in <i>Quercus dentata</i>.

Journal of fungi (Basel, Switzerland)·2026

Same author

Mechanisms of pruritus and advances in traditional Chinese medicine therapy (Review).

Molecular medicine reports·2026

Same author

Challenges and Opportunities of Oligomeric Acceptors Toward Efficient and Stable Organic Photovoltaics.

Advanced materials (Deerfield Beach, Fla.)·2026

Same author

Aerogel-involved triple-state viscoelastic fluidic materials enable high-efficiency dual-purpose energy management.

Nature communications·2026

Same author

Management of diabetic foot ulcers: polyherbal formulations and novel delivery systems for herbal active components.

Frontiers in pharmacology·2025

Same journal

Chlorinated VSLSs Surpass HCFCs in CFC-11-Equivalent Emissions for Ozone Layer Depletion in China.

Nature communications·2026

Same journal

Author Correction: Charge transfer in triphenylamine-tetrazine covalent organic frameworks for solar-driven hydrogen peroxide production.

Nature communications·2026

Same journal

Vegetation browning patterns under compound soil and atmospheric dryness in northern permafrost ecosystems.

Nature communications·2026

Same journal

Voltage imaging of CA1 pyramidal cells and SST+ interneurons reveals stability and plasticity mechanisms of spatial firing.

Nature communications·2026

Same journal

Radical-omics reveals the hydrogen-abstraction pathway of isoprene oxidation.

Nature communications·2026

Same journal

Toughening elastomer via sequentially activated multi-pathway energy dissipation.

Nature communications·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 8, 2026

Fabrication and Testing of Catalytic Aerogels Prepared Via Rapid Supercritical Extraction

Fabrication and Testing of Catalytic Aerogels Prepared Via Rapid Supercritical Extraction

Published on: August 31, 2018

Chemical O₂-generated aerogel-structured wearable microreactors.

Yuzhen Li^1,2, Yafei Ding², Yongji Li²

¹School of Nano-Tech and Nano-Bionics, University of Science and Technology of China, Hefei, PR China.

Nature Communications

|May 6, 2026

Summary

This summary is machine-generated.

Researchers developed wearable microreactors using armored aerogel fibers for on-demand oxygen generation. These devices offer improved fluid transport and textile integration, effectively treating hypoxia during in vivo trials.

More Related Videos

Aqueous Droplets Used as Enzymatic Microreactors and Their Electromagnetic Actuation

Aqueous Droplets Used as Enzymatic Microreactors and Their Electromagnetic Actuation

Published on: August 28, 2017

Encapsulating Cytochrome c in Silica Aerogel Nanoarchitectures without Metal Nanoparticles while Retaining Gas-phase Bioactivity

Encapsulating Cytochrome c in Silica Aerogel Nanoarchitectures without Metal Nanoparticles while Retaining Gas-phase Bioactivity

Published on: March 1, 2016

Related Experiment Videos

Last Updated: May 8, 2026

Fabrication and Testing of Catalytic Aerogels Prepared Via Rapid Supercritical Extraction

Fabrication and Testing of Catalytic Aerogels Prepared Via Rapid Supercritical Extraction

Published on: August 31, 2018

Aqueous Droplets Used as Enzymatic Microreactors and Their Electromagnetic Actuation

Aqueous Droplets Used as Enzymatic Microreactors and Their Electromagnetic Actuation

Published on: August 28, 2017

Encapsulating Cytochrome c in Silica Aerogel Nanoarchitectures without Metal Nanoparticles while Retaining Gas-phase Bioactivity

Encapsulating Cytochrome c in Silica Aerogel Nanoarchitectures without Metal Nanoparticles while Retaining Gas-phase Bioactivity

Published on: March 1, 2016

Area of Science:

Materials Science
Chemical Engineering
Biomedical Engineering

Background:

Wearable microreactors are crucial for life-sustaining processes like oxygen generation.
Existing materials lack the necessary robustness, textile integration, and efficient fluid transport.

Purpose of the Study:

To develop a wearable microreactor overcoming limitations in current materials.
To demonstrate on-demand oxygen generation for treating hypoxia.

Main Methods:

Fabrication of armored aramid aerogel hollow fibers with heat-shrink tubing.
Incorporation of a nanoconfined lubricant layer to reduce microfluidic drag.
Development of an oxygen-generating wearable microreactor prototype.

Main Results:

Achieved textile-compliant elasticity while preserving nanoporous structure.
Reduced microfluidic drag by up to 68.1% using a nanoconfined lubricant.
Demonstrated high space-time yield, 100% oxygen purity, and stable oxygen supply under stress.

Conclusions:

Established a novel materials paradigm for wearable microreactors.
Successfully alleviated acute hypoxia in in vivo trials at high altitude.
Overcame the trade-off between wearability and continuous-flow microreactor performance for on-body chemical synthesis.