Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
Atomic Nuclei: Magnetic Resonance01:05

Atomic Nuclei: Magnetic Resonance

The number of nuclear spins aligned in the lower energy state is slightly greater than those in the higher energy state. In the presence of an external magnetic field, as the spins precess at the Larmor frequency, the excess population results in a net magnetization oriented along the z axis. When a pulse or a short burst of radio waves at the Larmor frequency is applied along the x axis, the coupling of frequencies causes resonance and flips the nuclear spins of the excess population from the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Denoising of ASL Data Using Deep Learning Priors Generated From Distribution Remapping.

Magnetic resonance in medicine·2026
Same author

A frameshift variant in FAM129C contributes to achalasia through B cell responses against the GABA<sub>A</sub> receptor.

Nature communications·2026
Same author

Anti-GLDN antibody-associated CIDP (nodopathy): transient IVIg response and B-cell depletion remission.

BMC neurology·2026
Same author

A geometry aware framework enhances noninvasive mapping of whole human brain dynamics.

Nature biomedical engineering·2026
Same author

Rehabilitation paired with vagus nerve stimulation for motor function of chronic ischemic stroke patients in China: Study protocol of a multicenter randomized controlled trial (Repair Study).

Neuroprotection (Chichester, England)·2026
Same author

Dual association patterns between microglial activation and neuronal health in Alzheimer's disease: a whole-brain MRSI/PET study.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same journal

Inside the new political screening that's stalling NIH grants.

Nature·2026
Same journal

Europe's record heatwave: does the continent have a new climate?

Nature·2026
Same journal

Daily briefing: Humans and great apes giggle in the same rhythms.

Nature·2026
Same journal

The surprising career parallels between footballers and researchers.

Nature·2026
Same journal

I study World Cup penalty shoot-outs: they say a lot about the psychology of performance under pressure.

Nature·2026
Same journal

CRISPR's next act: the companies editing the epigenome to treat disease.

Nature·2026
See all related articles

Related Experiment Video

Updated: May 8, 2026

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
08:51

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

Multiplexed magnetic resonance imaging.

Yudu Li1,2, Rong Guo2,3, Yibo Zhao2

  • 1Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA.

Nature
|May 6, 2026
PubMed
Summary
This summary is machine-generated.

Multiplexed MRI (MRx) offers high-resolution, simultaneous mapping of multiple molecules, providing quantitative biomarkers for precise disease characterization. This advanced MRI technique enhances diagnosis and monitoring of neurological conditions.

More Related Videos

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
09:08

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging

Published on: February 27, 2011

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
09:57

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

Published on: July 25, 2022

Related Experiment Videos

Last Updated: May 8, 2026

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
08:51

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging
09:08

Multiple-mouse Neuroanatomical Magnetic Resonance Imaging

Published on: February 27, 2011

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
09:57

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy

Published on: July 25, 2022

Area of Science:

  • Biomedical Imaging
  • Radiology
  • Molecular Imaging

Background:

  • Magnetic resonance imaging (MRI) has advanced diagnostic radiology but is limited to macroscopic pathology.
  • Diseases like tumors and MS are heterogeneous, necessitating quantitative, non-invasive biomarkers for personalized medicine.
  • Current MRI lacks the resolution for detailed molecular and physiological tissue characterization.

Purpose of the Study:

  • Introduce multiplexed MRI (MRx) for simultaneous, high-resolution multiparametric mapping.
  • Demonstrate MRx's capability to acquire comprehensive quantitative biomarkers for whole-brain tissue characterization.
  • Evaluate MRx biomarkers for disease subtyping and lesion characterization in neurological conditions.

Main Methods:

  • Developed a novel MRI data acquisition and processing approach termed 'multiplexed MRI' (MRx).
  • Achieved simultaneous high-resolution mapping of multiple molecular, physiological, and structural parameters.
  • Applied MRx in standard clinical settings for comprehensive brain imaging.

Main Results:

  • MRx successfully obtained a wide array of quantitative biomarkers for the entire brain.
  • Demonstrated the utility of these biomarkers in defining a tissue state index for disease subtyping.
  • Showcased MRx's effectiveness in characterizing lesions in tumors and multiple sclerosis (MS).

Conclusions:

  • MRx provides unprecedented quantitative, multiparametric mapping capabilities for brain imaging.
  • This technology can significantly improve the diagnosis, monitoring, and therapeutic assessment of neurological diseases.
  • MRx has the potential to transform both clinical and research applications of brain MRI.