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Glial Cells

Glial Cells

Nervous Tissue: Glial Cells

Nervous Tissue: Glial Cells

Glia, or neuroglia, are vital support cells that assist neurons in their functions. The term "glia" originates from the Greek word for "glue," reflecting their role in holding the nervous system together. These cells can be categorized into six types: four in the central nervous system (CNS) and two in the peripheral nervous system (PNS).
The CNS glial cell includes the astrocytes, the oligodendrocytes, the microglia, and the ependymal cells.
Astrocytes are star-shaped glial cells that interact...

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Related Experiment Video

Updated: May 8, 2026

Time-Lapse Imaging of Migrating Neurons and Glial Progenitors in Embryonic Mouse Brain Slices

Time-Lapse Imaging of Migrating Neurons and Glial Progenitors in Embryonic Mouse Brain Slices

Published on: March 8, 2024

Gliogenesis in the mammalian cerebral cortex.

Parama Mitra¹, Shubha Tole¹

¹Tata Institute of Fundamental Research, Mumbai 400005, India.

Current Opinion in Genetics & Development

|May 6, 2026

Summary

Understanding glial cell production in the brain is key. New research reveals glial progenitors arise earlier than thought, impacting brain development and potential therapies.

Area of Science:

Neuroscience
Developmental Biology
Cell Biology

Background:

The cerebral cortex has diverse neuronal and glial cells.
Gliogenesis regulation and regional differences remain unclear.
Glial fate-restricted progenitors exist alongside multipotent progenitors.

Purpose of the Study:

Review recent studies on cortical gliogenesis in mice and humans.
Elucidate mechanisms regulating astrocyte and oligodendrocyte production.
Explore potential therapeutic applications.

Main Methods:

Review of recent mouse and human studies.
Analysis of progenitor cell behavior during development.
Comparative studies across cortical regions.

More Related Videos

A Model of Epileptogenesis in Rhinal Cortex-Hippocampus Organotypic Slice Cultures

A Model of Epileptogenesis in Rhinal Cortex-Hippocampus Organotypic Slice Cultures

Published on: March 18, 2021

Viral-mediated Labeling and Transplantation of Medial Ganglionic Eminence (MGE) Cells for In Vivo Studies

Viral-mediated Labeling and Transplantation of Medial Ganglionic Eminence (MGE) Cells for In Vivo Studies

Published on: April 23, 2015

Related Experiment Videos

Last Updated: May 8, 2026

Time-Lapse Imaging of Migrating Neurons and Glial Progenitors in Embryonic Mouse Brain Slices

Time-Lapse Imaging of Migrating Neurons and Glial Progenitors in Embryonic Mouse Brain Slices

Published on: March 8, 2024

A Model of Epileptogenesis in Rhinal Cortex-Hippocampus Organotypic Slice Cultures

A Model of Epileptogenesis in Rhinal Cortex-Hippocampus Organotypic Slice Cultures

Published on: March 18, 2021

Viral-mediated Labeling and Transplantation of Medial Ganglionic Eminence (MGE) Cells for In Vivo Studies

Viral-mediated Labeling and Transplantation of Medial Ganglionic Eminence (MGE) Cells for In Vivo Studies

Published on: April 23, 2015

Main Results:

Glial fate-restricted progenitors emerge during neurogenesis.
Progenitor timing influences glial cell production.
Region-specific variations in gliogenesis are observed.

Conclusions:

Gliogenesis is more complex than previously understood.
Understanding progenitor dynamics is crucial for cortical development.
Insights into gliogenesis may offer therapeutic avenues.