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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
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Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...

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Related Experiment Video

Updated: May 8, 2026

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
20:33

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Anastomotic Outcomes After Damage Control Laparotomy With Temporary Abdominal Closure.

Anthony J Duncan1, Reid Bartholomew1, Wade A Hopper1

  • 1Department of Surgery, School of Medicine & Health Sciences, University of North Dakota, Fargo, North Dakota.

The Journal of Surgical Research
|May 6, 2026
PubMed
Summary

Negative pressure wound therapy (NPWT) applied to anastomoses after damage control laparotomy does not increase leak risk. Anastomotic leak is more closely linked to patient acuity and time to closure.

Keywords:
Bowel anastomosisNegative pressure wound therapyOpen abdomenTemporary abdominal closure

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Published on: August 22, 2025

Area of Science:

  • Surgical innovation
  • Wound management
  • Gastrointestinal surgery

Background:

  • Negative pressure wound therapy (NPWT) is standard for temporary abdominal closure after damage control laparotomy.
  • The impact of NPWT on anastomotic leak rates is not well-defined.
  • This study investigates the association between NPWT and anastomotic leaks.

Purpose of the Study:

  • To determine if intra-abdominal NPWT exposure increases the risk of anastomotic leak.
  • To identify factors predicting anastomotic leak in patients undergoing damage control laparotomy.

Main Methods:

  • Retrospective cohort study of 225 patients undergoing emergent exploratory laparotomy with temporary abdominal closure (2013-2023).
  • Patients were stratified based on intra-abdominal NPWT application near a new anastomosis.
  • Multivariable regression analysis was used to assess predictors of anastomotic leak.

Main Results:

  • 93 patients (41%) received NPWT near their anastomosis.
  • Anastomotic NPWT exposure was not significantly associated with an increased risk of leak.
  • Physiological Emergency Surgery Acuity Score and days to fascial closure were independent predictors of anastomotic leak.

Conclusions:

  • Intra-abdominal NPWT is not an independent risk factor for anastomotic leak in damage control laparotomy.
  • NPWT can be used judiciously for bowel anastomoses when clinically indicated.
  • Anastomotic leak risk is primarily driven by patient physiological status and illness severity.