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Pediatric to adult transition in chronic kidney disease: a scoping review

Zachariah Alkhayri1, Rama Safadi1, Andrea Varghese1

  • 1College of Medicine, Northeast Ohio Medical University, Rootstown, OH, USA.

BMC Nephrology
|May 7, 2026
PubMed

Insights

Effective transition from pediatric to adult care is crucial for children with chronic kidney disease (CKD). Structured models and early preparation improve outcomes by addressing patient, provider, and system barriers.

Area of Science:

  • Pediatric Nephrology
  • Healthcare Transition
  • Chronic Kidney Disease Management

Background:

  • Pediatric chronic kidney disease (CKD) presents unique challenges compared to adult CKD.
  • Transitioning from pediatric to adult care is a critical period with risks of nonadherence, loss to follow-up, and graft failure.
  • Existing transition models vary in their approaches to address these challenges.

Conclusions:

  • Effective transition is vital for improving pediatric and adult health outcomes in CKD.
  • Future research should explore standardized protocols (e.g., Six Core Elements) and technology integration.
  • System-supported, evidence-based transition models are essential for successful care transfer.
Abstract

Keywords:
Adolescent health servicesAdolescentsChronic kidney diseasePatient compliancePediatricsTransition of careTransition to adult careTransitional care models

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