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Age-varying DNA methylation patterns associated with blood pressure in mid-to-late adulthood

Gang Xu1, Xiaowei Zhuang2,3, Amei Amei4

  • 1Laboratory of Neurogenetics and Precision Medicine, College of Sciences, University of Nevada Las Vegas, Las Vegas, NV, USA. gang.xu@unlv.edu.

Clinical Epigenetics
|May 7, 2026
PubMed
Summary

DNA methylation patterns in blood dynamically change with age, influencing blood pressure. These age-dependent epigenetic changes, particularly in mid-to-late adulthood, may indicate vascular aging and inform cardiovascular risk biomarkers.

Keywords:
Age‑dependent epigenetic regulationAge‑varying DNA methylation effectBlood pressureEpigenome‑wide association study (EWAS)Longitudinal cohort

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