Related Experiment Videos
Estimating Discrete Latent Variable Models Using Amortized Variational Inference
Karel Veldkamp1, Raoul Grasman1, Dylan Molenaar2
1Psychology, https://ror.org/04dkp9463Universiteit van Amsterdam, Netherlands.
Abstract:
Recent research shows that amortized variational inference (AVI) can be used to efficiently estimate high-dimensional latent variable models on large datasets. However, its use has remained limited to item response theory (IRT), and generalizing the approach to discrete latent variable models is not straightforward. We propose two ways to deal with this problem. In an initial simulation, we verify that these approaches can be used to estimate simple discrete latent variable models, such as latent class analysis and the generalized deterministic inputs, noisy and gate model. In these cases, AVI provides accurate parameter estimates, although the computational advantage over marginal maximum likelihood (MML) and standard variational inference (VI) is limited. We then apply the same approach to estimate mixture IRT models. In this case, AVI is computationally faster than MML estimation and standard VI. To demonstrate the practical applicability of our AVI approach, we use it to fit a seven-dimensional mixture IRT model to a narcissism inventory. Whereas quadrature-based methods cannot feasibly estimate models of this dimensionality, the efficient AVI approach even allows for computation of bootstrapped standard errors. We provide our code, along with an easy-to-use tool for fitting these models to new datasets.
Related Concept Videos
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation
On...
Estimation of the Physical Quantities
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
Variability: Analysis
The range is a simple measure of variability, indicating the difference between the highest and...
Prediction Intervals
However, the point estimate is most likely not the exact value of the population parameter, but close to it. After calculating point estimates, we construct interval estimates, called confidence intervals or prediction intervals. This prediction interval comprises a range of values unlike the point estimate and is a better predictor of the observed sample value, y.
The...
Multicompartment Models: Overview
These models offer a more comprehensive representation of drug behavior in the body than one-compartment models. They accommodate the complexity of drug distribution,...