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Published on: October 27, 2023
PixelDeck: A local-first media library manager for biomedical imaging
1Department of Oncology, Wayne State University School of Medicine, Detroit, MI, USA.
Biorxiv : the Preprint Server for Biology
|May 7, 2026
Summary
PixelDeck is an open-source application that organizes and browses large biomedical image and video libraries locally. It efficiently manages diverse imaging collections, aiding dataset exploration and preparation for analysis.
Area of Science:
- Biomedical Imaging
- Computational Pathology
- Digital Pathology
Background:
- Biomedical imaging workflows generate vast amounts of derived image and video data.
- Current methods for managing these assets are often inefficient due to dispersed storage.
- Challenges include retrieval, deduplication, and figure assembly for large media collections.
Purpose of the Study:
- To introduce PixelDeck, an open-source, local-first browser application for organizing and interactively browsing biomedical image and video libraries.
- To provide an efficient and scalable solution for managing high-volume, heterogeneous imaging collections on standard hardware.
- To streamline dataset exploration and preparation for downstream analysis in biomedical research.
Main Methods:
- PixelDeck utilizes a modular ingestion pipeline with recursive folder import and SHA-256-based duplicate detection.
- It features metadata extraction, thumbnail/preview generation, and full-text search within a responsive interface.
- The system employs a Next.js/React frontend, SQLite metadata store (via Prisma), managed local storage, and asynchronous background workers for scalable processing.
Main Results:
- Benchmark imports using public histopathology datasets (PanopTILs, SICAPv2, PanNuke) demonstrated reproducible import behavior and ingestion metrics.
- Duplicate detection and metadata extraction were efficiently handled.
- Embedding-based analysis confirmed dataset-level separation based on image characteristics, validating the system's organization capabilities.
Conclusions:
- PixelDeck offers an efficient and scalable local curation layer for biomedical imaging collections.
- The application facilitates streamlined dataset exploration and preparation for downstream analysis.
- It addresses the challenges of managing dispersed and large-volume imaging assets in modern research workflows.
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