Comparison of anterior segment parameter measurements between Sirius Plus and Pentacam AXL

This cross-sectional study compared the differences, consistencies, and correlations of the measurements of anterior segment biological parameters between Sirius Plus and Pentacam AXL in a healthy population with myopia.

Eighty patients with myopia (80 eyes) scheduled for refractive surgery at the Ophthalmology Department of the Third People's Hospital of Dalian from December 2024 to June 2025 were included. One eye was randomly selected for each participant, and measurements were taken using Sirius Plus and Pentacam AXL. Fourteen parameters related to the anterior segment were extracted.

The differences in the measurements for anterior flat keratometry, anterior vertical/horizontal astigmatism, and anterior oblique astigmatism at 45° between the two devices were not significant, whereas those for the other parameters were significant. The intraclass correlation coefficient values for anterior flat keratometry, anterior steep keratometry, and white-to-white were 0.965, 0.963, and 0.932, respectively. The goodness-of-fit analysis showed that the R ² values for the anterior flat keratometry, anterior steep keratometry, central corneal thickness, white-to-white, corneal volume, and anterior chamber depth were all >0.85, which demonstrated a strong correlation.

Anterior corneal keratometry and white-to-white had good correlation and consistency, indicating they are suitable mutual reference points for clinical practice.