Related Experiment Video
Updated: May 8, 2026

07:43
Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Skull Base Reconstruction Following Endoscopic Pituitary Surgery: A Global Survey
Fabio P Gazmenga1, Daniel M Prevedello2, Ricardo L Carrau3
1Department of Otorhinolaryngology, University of Campinas, Campinas, São Paulo, Brazil.
Summary
Global pituitary surgery centers show varied reconstruction strategies. Multilayer reconstruction and autologous grafts are trending, with otolaryngologist presence influencing choices for endoscopic endonasal transsphenoidal pituitary surgery.
Area of Science:
- Neurosurgery
- Otolaryngology
- Skull Base Surgery
Background:
- Endoscopic endonasal transsphenoidal pituitary surgery is a complex procedure.
- Reconstruction of the surgical site is a critical step influencing patient outcomes.
- Practices for reconstruction vary significantly among surgical centers worldwide.
Purpose of the Study:
- To investigate global practices in the reconstruction phase of endoscopic endonasal transsphenoidal pituitary surgery.
- To understand the rationale and strategies employed by different pituitary surgery centers.
- To identify factors influencing reconstruction technique selection.
Main Methods:
- A global survey was conducted among representatives of pituitary surgery centers.
- An online 15-question questionnaire was used to gather data on reconstruction strategies.
- Data were collected from 121 centers across 36 countries.
Main Results:
- A preference for multilayer reconstruction was noted across all presented scenarios.
- Autologous materials (fat grafts, fascia lata, pedicled flaps) were more frequently used in cases of cerebrospinal fluid (CSF) leak and extended approaches.
- Centers with otolaryngology specialists showed a greater tendency to use pedicled flaps, especially for cases without expected CSF leak.
Conclusions:
- Significant variability exists in pituitary/skull base surgery reconstruction strategies globally.
- Trends indicate a move towards multilayer reconstruction, nasoseptal flaps, and autologous grafts.
- The involvement of an otolaryngologist impacts institutional reconstruction strategies.
