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Leveraging Artificial Intelligence for Personalized Pharmacotherapy: Emerging Roles for Pharmacists.
Adileidy Quero1, Randall Knoebel2, Amir Tahmasebi3
1Department of Lloyd L. Gregory School of Pharmacy, Palm Beach Atlantic University, West Palm Beach, FL, USA.
Journal of Pharmacy Practice
|May 7, 2026
Summary
Pharmacists can use precision medicine and artificial intelligence (AI) to optimize drug therapy. AI and pharmacogenomics offer valuable tools for personalized pharmacotherapy, improving patient outcomes across various disease states.
Area of Science:
- Pharmacogenomics and Artificial Intelligence in Pharmacotherapy
Background:
- Precision medicine and AI are transforming healthcare, offering new avenues for optimizing drug therapy.
- Pharmacists play a crucial role in integrating advanced tools into patient care.
- Challenges include accessibility of multi-omics data and ethical considerations.
Purpose of the Study:
- To explore how pharmacists can utilize precision medicine and AI for optimal pharmacotherapy.
- To identify the roles of AI in acute care, chronic disease management, and rare diseases.
- To propose strategies for leveraging these technologies in clinical practice.
Main Methods:
- A narrative literature review was conducted using PubMed (2020-2025).
- Search terms included precision medicine, AI, machine learning, predictive/prescriptive analytics, and pharmacogenomics.
- Relevant English-language studies and reviews were considered.
Main Results:
- Pharmacogenomics, integrated with multi-omics, is crucial for safe and effective therapy.
- AI applications, including predictive and machine learning analytics, enhance pharmacotherapy evaluations.
- Big data serves as an alternative for clinical decision support when multi-omics data is unavailable.
Conclusions:
- Pharmacists should be empowered to adopt innovative strategies like pharmacogenomics and AI.
- These technologies provide valuable tools for optimizing pharmacotherapy.
- Ethical standards and equitable access must be maintained while pursuing personalized medicine.
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