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Paroxysmal sympathetic hyperactivity secondary to hypoglycemic encephalopathy: A case report
Yushi Kohzuki1, Junpei Yamamoto1, Yuki Kaminaga1
1Division of Diabetes, Metabolism and Endocrinology, Osaki Citizen Hospital, Osaki, Japan.
Journal of Diabetes Investigation
|May 7, 2026
Summary
A patient experienced a hypoglycemic coma and persistent altered consciousness. This led to a diagnosis of hypoglycemic encephalopathy, complicated by rare paroxysmal sympathetic hyperactivity (PSH).
Area of Science:
- Neurology
- Endocrinology
- Critical Care Medicine
Background:
- Hypoglycemic coma can lead to persistent neurological deficits.
- Hypoglycemic encephalopathy is a serious complication of severe hypoglycemia.
- Paroxysmal sympathetic hyperactivity (PSH) is a rare but critical condition.
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