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Updated: May 8, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

Novel treatment strategies in cardiogenic shock: an update on ongoing clinical trials

Mireia Padilla-Lopez1, Francesca Manicone2,3, Sarah L D Holle4

  • 1Cardiology Department, IIB-SantPau, Hospital de la Santa Creu I Sant Pau, Universidad Autónoma de Barcelona, Barcelona, Spain. mpadillal@santpau.cat.

Heart Failure Reviews
|May 7, 2026
PubMed

Insights

Managing cardiogenic shock is difficult, with high mortality and no standard treatments. This review covers clinical trials on new drugs, mechanical support, and monitoring to improve patient outcomes.

Area of Science:

  • Cardiology
  • Critical Care Medicine

Background:

  • Cardiogenic shock presents significant clinical challenges with high mortality rates.
  • Current therapeutic strategies for cardiogenic shock lack standardization.

Purpose of the Study:

  • To provide a comprehensive overview of ongoing clinical trials for cardiogenic shock treatment.
  • To synthesize evidence on novel pharmacological therapies, mechanical circulatory support, and hemodynamic monitoring.

Main Methods:

  • Review of ongoing clinical trials in cardiogenic shock treatment.
  • Categorization of trials into pharmacological, mechanical support, and monitoring strategies.

Main Results:

  • Identified key research directions in cardiogenic shock management.
  • Highlighted emerging data with potential to influence future clinical practice.

Conclusions:

  • Further research and clinical trials are essential for advancing cardiogenic shock treatment.
  • Optimizing pharmacological therapies, mechanical support, and monitoring are crucial for improving patient outcomes.
Keywords:
Cardiogenic shockClinical trialsHeart failureMechanical circulatory supportMyocardial infarction

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