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Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney
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Pale blue inclusions on light microscopy as a clue to light chain proximal tubulopathy

Shoko Ochiai1, Masao Kikuchi1, Koichi Kaikita1

  • 1Division of Cardiovascular Medicine and Nephrology, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.

Journal of Nephrology
|May 7, 2026
PubMed
Abstract

No abstract available in PubMed .

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Lampbrush Chromosomes01:51

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In 1882, Flemming observed lampbrush chromosomes (LBC) in salamander eggs. Later in 1892, Rückert observed LBCs in shark egg cells and coined the term "lampbrush chromosomes" because they looked like brushes used to clean kerosene lamps.
LBCs are made up of two pairs of conjugating homologous chromatids. Each chromatid consists of alternatively positioned regions of condensed-inactive chromatin and loosely placed-active side loops, which can be contracted and extended. The loops resemble the...

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