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Updated: May 9, 2026

Synthesis of a Thiol Building Block for the Crystallization of a Semiconducting Gyroidal Metal-sulfur Framework
Published on: April 9, 2018
Light-Induced Site-Selective Functionalization of Tertiary C(sp3)-H Bonds via a Synergistic System Combining TBADT
Wenbin Xu1, Jiajun Wang2, Liying Yu1
1Department of Chemistry, Education Department of Jilin Province Key Laboratory of Advanced Organic Molecule Synthesis and Application, Jilin University of Chemical Technology, Jilin 132022, People's Republic of China.
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A site-selective functionalization of C(sp3)-H bonds is described. Electrophilic alkenes and alkynes are used to perform the site-selective functionalization of tertiary C(sp3)-H bonds enabled by merging a tetrabutylammonium decatungstate (TBADT) as a hydrogen atom abstractor (HAA) and a thiol as a hydrogen atom donator (HAD) under light irradiation. Excess use of substrates could be avoided; greater than 20:1 site selectivity and up to 84% yield could be obtained with the help of 2,4,6-tri-tert-butylbenzenethiol.
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