Related Experiment Video

Updated: May 9, 2026

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
05:37

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

G-Quadruplex stabilization impairs early embryo development by impairing DNA replication and inducing R-loops and DNA

Ke Xu1,2,3, Chao Li1, Youhui Lu1

  • 1Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, 510317, China.

Reproduction (Cambridge, England)
|May 7, 2026
PubMed

Keywords:
Braco-19DNA damageDNA replicationG4 stabilizationPDSR-loopmouse embryo

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