Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Atomic Force Microscopy

Atomic Force Microscopy

Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Belowground clonal expansion and biomass allocation of Phragmites australis along a sand burial gradient in mobile dunes.

BMC plant biology·2026

Same author

Dual-Protein Intervention in CT26 Tumor-Bearing Mice: A Preliminary Evaluation of Its Effects on Anti-Tumor Efficacy of 5-Fluorouracil and Immune Responses.

Nutrients·2026

Same author

Physicochemical Properties, Rheological Characteristics, Flavor Profile and Antioxidant Activity of Fermented Plant-Based Alternative to Yoghurt from <i>Avena sativa</i> L. and <i>Prunus dulcis</i> (Mill.) D. A. Webb.

Foods (Basel, Switzerland)·2026

Same author

Novel BLT1 inhibitor baeckein E ameliorates LPS-induced acute lung injury through ferroptosis inhibition.

Phytomedicine : international journal of phytotherapy and phytopharmacology·2026

Same author

Genetic regulatory landscape of gene expression during leaf and stem development in common tobacco.

Journal of genetics and genomics = Yi chuan xue bao·2026

Same author

Persistent histone H3K27 acetylation contributes to excessive scar formation after spinal cord injury through the regulation of microglial cholesterol accumulation.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics·2026

Same journal

Immunofluorescence study and morphometric analysis of collagen-IV in the exchange tissue of the quail (Coturnix coturnix) lung by confocal laser scanning microscopy.

Micron (Oxford, England : 1993)·2026

Same journal

Micromorphological study of leaf surfaces structures in selected Crataegus L. (Rosaceae) species using light, scanning electron, and confocal laser microscopy.

Micron (Oxford, England : 1993)·2026

Same journal

3D reconstruction of the nymphal feeding apparatus of Philaenus spumarius.

Micron (Oxford, England : 1993)·2026

Same journal

The influence of physicians and surgeons on Leeuwenhoek's observations of crystal formation.

Micron (Oxford, England : 1993)·2026

Same journal

Distribution of telocytes in the choroid (eye) of a teleost: An ultrastructural observation.

Micron (Oxford, England : 1993)·2026

Same journal

SEM-EDAX: A tool for microanalytical elemental mapping in butterfly wing scales.

Micron (Oxford, England : 1993)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 9, 2026

Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid

Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid

Published on: December 20, 2016

Enhancing higher-order modal responses in atomic force microscopy with a segmented constraint methodology.

Haowei Sun¹, Jianqiang Qian¹, Yanan Chen¹

¹Beihang University, No. 37, Xueyuan Road, Haidian District, Beijing, 100191, Beijing, China.

Micron (Oxford, England : 1993)

|May 7, 2026

Summary

This summary is machine-generated.

A new segmented fixture design enhances bimodal atomic force microscopy (bimodal-AFM) by boosting higher eigenmode response. This improves nanoscale material characterization on polymer surfaces in ambient conditions.

Keywords:

Atomic force microscopy Coupled system Finite element simulation Higher-order eigenmodes Multi-frequency

More Related Videos

High-Speed Atomic Force Microscopy Imaging of DNA Three-Point-Star Motif Self Assembly Using Photothermal Off-Resonance Tapping

High-Speed Atomic Force Microscopy Imaging of DNA Three-Point-Star Motif Self Assembly Using Photothermal Off-Resonance Tapping

Published on: March 22, 2024

Related Experiment Videos

Last Updated: May 9, 2026

Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid

Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid

Published on: December 20, 2016

High-Speed Atomic Force Microscopy Imaging of DNA Three-Point-Star Motif Self Assembly Using Photothermal Off-Resonance Tapping

High-Speed Atomic Force Microscopy Imaging of DNA Three-Point-Star Motif Self Assembly Using Photothermal Off-Resonance Tapping

Published on: March 22, 2024

Area of Science:

Materials Science
Nanotechnology
Surface Science

Background:

Bimodal atomic force microscopy (bimodal-AFM) is crucial for nanoscale material characterization.
Performance is often limited in ambient conditions due to weak higher eigenmode response.

Purpose of the Study:

To enhance the performance of bimodal-AFM in atmospheric environments.
To improve nanoscale material property mapping.

Main Methods:

Introduction of a novel segmented fixture design for the atomic force microscope probe.
Adjustment of excitation boundary conditions to amplify higher eigenmodes.

Main Results:

Significant enhancement of the second eigenmode's vibrational amplitude.
Maintained sensitivity of the base mode.
Achieved a 2.8-fold increase in higher eigenmode response compared to conventional bimodal-AFM.

Conclusions:

The segmented fixture design offers a practical, hardware-based solution to improve bimodal-AFM performance.
This approach expands the application scope of bimodal-AFM for surface characterization under ambient conditions without complex processing.