Related Experiment Video
Updated: May 9, 2026
08:23
Phenotypic Analysis of Rodent Malaria Parasite Asexual and Sexual Blood Stages and Mosquito Stages
Published on: May 30, 2019
Malaria in Children at 9 US Hospitals: 2016-2023
Sesh Alexander Sundararaman1, Brianne Roper1,2, Amy K F Davis3
1Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Pediatrics
|May 7, 2026
Summary
Delayed diagnosis of imported pediatric malaria in the US is common, increasing severe disease risk. Prompt diagnosis and chemoprophylaxis are vital for better outcomes in children.
Area of Science:
- Infectious Diseases
- Global Health
- Pediatrics
Background:
- Imported pediatric malaria presents a public health challenge in non-endemic regions.
- Understanding trends and risk factors is crucial for effective management.
Purpose of the Study:
- To describe imported pediatric malaria cases in the US from 2016-2023.
- To identify patient demographics, clinical outcomes, and risk factors for severe disease.
Main Methods:
- Retrospective descriptive study.
- Analysis of 171 pediatric malaria cases from 9 US hospitals (2016-2023).
- Evaluation of patient demographics, symptoms, and diagnostic timelines.
Main Results:
- Most cases involved travel to West Africa; fever and abdominal symptoms were common.
- 32% of children had severe malaria.
- Delayed diagnosis (26%) was frequent and a significant risk factor for severe outcomes.
Conclusions:
- Delayed diagnosis of imported pediatric malaria is a critical issue in the US.
- Prompt diagnosis and malaria chemoprophylaxis are essential for reducing morbidity and improving patient outcomes.
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