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Related Concept Videos

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

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Updated: May 9, 2026

Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing
08:12

Synthesis and Operation of Fluorescent-core Microcavities for Refractometric Sensing

Published on: March 13, 2013

Edible optical microcavities for optical barcoding, authentication, and sensing.

Abdur Rehman Anwar1,2, Slavko Kralj1, Matjaž Humar3,4,5

  • 1J. Stefan Institute, Jamova 39, SI-1000, Ljubljana, Slovenia.

Scientific Reports
|May 7, 2026
PubMed
Summary
This summary is machine-generated.

Researchers developed edible optical microcavities using chlorophyll-coated microspheres for secure product authentication. These microcavities act as unique optical barcodes, enhancing food and pharmaceutical safety and traceability.

Keywords:
Edible materialsOptical barcodesPhysical unclonable functionsSensorsWhispering gallery modes

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Area of Science:

  • Materials Science
  • Optical Engineering
  • Food Science

Background:

  • Food and pharmaceutical safety face challenges from counterfeiting, with external anti-counterfeiting measures being vulnerable.
  • Incorporating security features directly into edible products offers a more robust solution.

Purpose of the Study:

  • To develop edible whispering-gallery mode (WGM) microcavities for secure labeling and sensing in consumable products.
  • To demonstrate the potential of these microcavities as edible optical barcodes and physical unclonable functions (PUFs).

Main Methods:

  • Fabrication of chlorophyll-coated silica microspheres supporting stable WGM resonances.
  • Embedding microspheres in agarose matrices to create size-specific spectral signatures.
  • Utilizing size variations for edible physical unclonable functions (PUFs).
  • Integrating microcavities into pH-responsive hydrogels for sensing applications.

Main Results:

  • Stable WGM resonances with quality factors of 2,000–10,000 were achieved.
  • Microsphere diameters were determined with ~40 nm precision.
  • Edible optical barcodes with stability exceeding six months were demonstrated.
  • Sugar concentration and pH sensing capabilities were shown with high accuracy.

Conclusions:

  • Edible WGM microcavities offer a multifunctional platform for secure labeling and anti-counterfeiting.
  • This technology enhances the safety, authenticity, and traceability of food and pharmaceutical products.
  • The developed microcavities enable sensitive environmental monitoring within consumable goods.