Related Experiment Video
Updated: May 9, 2026

06:07
Measuring Mitochondrial Function of Naïve and Effector CD8 T Cells
Published on: March 28, 2025
Author Correction: Early methionine availability attenuates T cell exhaustion
Piyush Sharma1, Ao Guo2,3, Suresh Poudel2
1Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA. piyush.sharma@stjude.org.
Nature Immunology
|May 7, 2026
Summary
No abstract available in PubMed .
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T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
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