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Updated: May 9, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

Managing Fever Without Source in Well-appearing Young Infants: A Pragmatic Approach

Ingmar Fortmann1,2, Christoph Härtel2,3, Arne Simon4,5

  • 1From the Department of Pediatrics, University Hospital Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.

The Pediatric Infectious Disease Journal
|May 8, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
fever without sourceinvasive bacterial infectionsepsiswell-appearing infant

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A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
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Types of Fever

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A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...
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