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Case Report: A giant dedifferentiated liposarcoma in the retroperitoneum
Jinglin Xu1, Linru Yang2, Haoyang Zhang1
1Lanzhou University, Lanzhou, Gansu, China.
Frontiers in Oncology
|May 8, 2026
Summary
A large retroperitoneal dedifferentiated liposarcoma (DDLPS) was resected in a 60-year-old woman. Treatment included surgery, radiotherapy, chemotherapy, and immunotherapy, leading to a good recovery.
Area of Science:
- Surgical Oncology
- Medical Oncology
- Radiotherapy
- Genetics
Background:
- Retroperitoneal liposarcoma is a rare malignancy.
- Dedifferentiated liposarcoma (DDLPS) is an aggressive subtype.
- Large tumors can cause significant mass effect and invade adjacent organs.

