Related Experiment Video
Updated: May 9, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Scientific trends in obstructive sleep apnea biological and clinical assessment indicators: a bibliometric analysis
Shudan Deng1, Haixia Fan2, Lu Zhai1
1Second College of Clinical Medicine, Shanxi Medical University, Taiyuan, Shanxi, China.
Aims:
Obstructive sleep apnea (OSA) is characterized by diverse biological and clinical disturbances, yet no study has systematically examined scientific developments related to its objective assessment measures. This study aimed to map the development, research hotspots, and emerging trends related to biological and clinical assessment indicators in OSA.
Materials And Methods:
Publications indexed in the Web of Science Core Collection and Scopus from 2000 to 2025 were reviewed. A total of 1,793 articles were analyzed using VOSviewer, CiteSpace, the R bibliometrix package, and Python. The analysis assessed publication and citation trends, country contributions, keyword co-occurrence, and thematic evolution to map global research patterns in OSA assessment.
Results:
The number of publications increased steadily over time, reflecting growing research interest in multidimensional assessment approaches. Research themes have evolved from general inflammatory and metabolic markers toward more mechanistic and clinically oriented indicators, including oxidative stress pathways, circulating biomarkers, and cerebrovascular or cognitive related measures.
Conclusions:
Current research increasingly emphasizes integrated biological and clinical assessment frameworks for better characterization of OSA. Future studies should focus on validation, methodological standardization, and the integration of multiple assessment domains to facilitate clinical translation.
Related Concept Videos
Sleep Apnea
The condition is more prevalent among...
Assessment of Ventilation I: Respiratory Rate
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:
Other Pulmonary Disorders
Assessment of Respiration
Subjective Assessment: Nurses interview the patient to gather information directly during the subjective assessment. It includes questions about the individual's medical history, medications, and symptoms, focusing on past respiratory conditions like asthma or COPD,...
Respiratory Assessment: Purpose and Indications
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
Physical Assessment of the Respiratory Tract II: Inspection
Chest Configuration
The chest configuration can...

