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Related Concept Videos

Ethical Dilemmas II01:30

Ethical Dilemmas II

Resolving an ethical dilemma in healthcare involves a systematic approach that considers every aspect of the issue, respecting both the patient's needs and values and the healthcare professional's ethical obligations. Here are potential steps to resolve an ethical dilemma:
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Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Ethics in Research

Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
Embryonic Stem Cells00:58

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.

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Related Experiment Video

Updated: May 9, 2026

Pre-clinical Model of Cardiac Donation after Circulatory Death
06:26

Pre-clinical Model of Cardiac Donation after Circulatory Death

Published on: August 2, 2019

Supporting Informed Surrogate Decision-Making in Deceased Donor Intervention Research: Co-Creating Educational

Nicholas Murphy1,2, Charles Weijer1,2,3, Janice Beitel4

  • 1Department of Philosophy, Western University, London, ON, Canada.

Critical Care Explorations
|May 8, 2026
PubMed
Summary

Developing organ donation consent materials with families improves comprehension and trust. This collaborative approach enhances informed consent for deceased donor intervention research, supporting ethical practices.

Keywords:
decision-makinginformed consenttissue and organ procurementtrust

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Last Updated: May 9, 2026

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Area of Science:

  • Organ transplantation research
  • Informed consent in critical care

Background:

  • Deceased donor intervention research requires valid informed consent from surrogate decision-makers.
  • Challenges in obtaining consent include family grief, decisional burden, and intervention complexity, impacting comprehension, trust, and voluntariness.

Purpose of the Study:

  • To describe a collaborative model for co-creating consent and educational materials with deceased donors' family members.
  • To outline a co-creation process and share practical lessons learned for improving informed consent in donor intervention trials.

Main Methods:

  • A collaborative model was developed for co-creating consent and educational materials with deceased donor families.
  • The process involved iterative refinement, emphasizing trust, visual communication, and standardization.

Main Results:

  • Materials co-created with donor families enhanced clarity, relevance, and sensitivity.
  • The approach supported research coordinators and demonstrated a scalable framework for ethically robust research.

Conclusions:

  • Partnership with donor families in developing consent materials improves the informed consent process.
  • This model facilitates ethically sound deceased donor intervention research and enhances organ donation and transplantation outcomes.