Room-Temperature Aldol Condensation for n-Type Elastic-Plastic Organic Mixed Ionic-Electronic Conductors

The emergence of bioinspired electronics highlights the organic mixed ionic-electronic conductors (OMIECs) as key materials for mimicking biological systems. However, their practical deployment is hindered by an unsustainable synthesis, structural defects, and poor mechanical resilience. Here, we present a room-temperature, metal-free aldol condensation catalyzed by triethylamine, using a flexible linker embedding engineering (FLEE) strategy to synthesize a new class of n-type OMIECs with broad substrate compatibility. This approach yields defect-reduced, biocompatible OMIECs by integrating rigid conjugated backbones with soft oligoethylene glycol (OEG) linkers. The resulting materials bridge small-molecule crystallinity with polymerlike elasticity, suggesting an improved balance between crystallinity and mechanical compliance. They represent the first n-type elastic-plastic OMIECs, maintaining high performance in organic electrochemical transistors (OECTs) and synaptic transistors (OESTs) and enabling stable synaptic plasticity and mechanical flexibility for neuromorphic computing. Our work establishes a sustainable platform for next-generation wearable bioinspired electronics.