Related Experiment Video
Updated: May 10, 2026
09:20
Generation of Multicellular Human Primary Endometrial Organoids
Published on: October 4, 2019
From breakdown to repair: A human organoid model of menstruation
1Department of Physiology and Membrane Biology, University of California Davis, Davis, CA, USA; Department of Obstetrics and Gynecology, University of California Davis, Davis, CA, USA.
Cell Stem Cell
|May 8, 2026
Abstract:
Menstruation entails repeated cycles of cyclical shedding and scarless regeneration of the endometrium, yet the precise cellular states underlying this process have remained poorly defined. In this issue, Nikolakopoulou et al. establish an in vitro menstrual cycle (IVMC) protocol using human endometrial organoids, revealing WNT7A as a central regulator of epithelial regeneration.
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