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Updated: May 10, 2026

Microfluidic-based Synthesis of Covalent Organic Frameworks (COFs): A Tool for Continuous Production of COF Fibers and Direct Printing on a Surface
Published on: July 10, 2017
Two-Dimensional Covalent Organic Framework Membranes: Multi-Scale Design and Forward-Looking Perspectives
Sheng Yuan1, Shilin Guo1, Teng Liu1
1Key Laboratory for Green Chemical Technology of Ministry of Education, School of Chemical Engineering and Technology, Tianjin University, Tianjin, China.
Abstract:
Two-dimensional covalent organic frameworks (2D COF) are attracting considerable attention as an emerging platform for membrane materials due to their well-defined nanochannels, exceptional structural designability, high stability, and versatile synthesis routes. This review aims to establish a multiscale design framework to accelerate the advancement of 2D COF membranes. First, we systematically discuss engineering principles ranging from molecular-scale monomer design, crystallinity control, transport-channel engineering, and stacking modulation to macroscopic membrane processing. Second, we summarize and highlight recent progress in 2D COF membranes for various separation-related applications, including gas separation, liquid purification, ion sieving, and energy storage and conversion. Finally, we identify key scientific and technological challenges and propose a roadmap to bridge laboratory innovations with industrial deployment. The outlined multiscale design principles and forward-looking perspectives are expected to guide the rational development of 2D COF membranes for diverse environmental and energy applications.
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