Related Experiment Video
Updated: May 11, 2026

Assessment of Chemical Toxicity in Adult Drosophila Melanogaster
Published on: March 24, 2023
Toxicologic Pathology Forum Opinion*: In Defense of Scientific Freedom
Rani S Sellers1, Richard A Peterson2, Brad Bolon3
1The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Abstract:
Science is a lodestar in the search for knowledge to successfully steer societies through the stormy seas of a changeable world. Scientists are the navigators, using experiments and reason to find answers that expand basic knowledge and influence applications (e.g., public policymaking and risk assessment). An understanding of the scientific method generally and in-depth comprehension of a scientific field specifically are limited in many adults today, both among the public and in cultural and political leaders. Accordingly, scientists must vigorously defend science by upholding two core principles: (1) scientists must be free to ask and answer questions without concern for subjective cultural, ideological, and political constraints, and (2) the diverse perspectives of scientists based on their unique experiences are essential drivers of scientific innovation and attainment. Toxicologic pathologists have a responsibility to uphold these principles, whether their actions are directed to their institutions, the entire toxicologic pathology profession, or the scientific community and society. Concrete actions available to individual pathologists include communicating support for intellectual freedom of thought and association (orally or in writing) among colleagues or to the public as well as providing services (professional society governance, public political office, scientific advocacy, teaching, etc.) that maintain these principles.
More Related Videos
17:28Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation
Published on: June 17, 2015
06:00Experimental Protocol for Using Drosophila As an Invertebrate Model System for Toxicity Testing in the Laboratory
Published on: July 10, 2018
Related Concept Videos
Toxicity Testing in Animals
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Drug Toxicity: Overview
Toxicokinetics: Overview
Bioactivation and Tissue Toxicity
The Scientific Method
Generally, predictions are tested using carefully-designed experiments. Based on the outcome of these...